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April 12, 2003

Neuroptix Data Published in Peer-Reviewed Lancet Article

A-beta aggregates found in lens fiber cells of the eye

April 12, 2003 - Investigators from the Massachusetts General Hospital and the Brigham and Women's Hospital in Boston have found that a peptide known as A-b, a hallmark of Alzheimer's disease, has been found to form aggregates in the lens of the eye in AD patients which are analogous to the deposits in the brain which are thought to be a principal cause of disability in the disease.

Drs. Lee Goldstein and Leo Chylack and their colleagues at the Harvard-associated hospitals published their findings today in Lancet (Lancet 2003; 361: 1258–65) in an article entitled "Cytosolic amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease."

For more information, see:

  • Cytosolic Β-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease
  • Lee E Goldstein, Julien A Muffat, Robert A Cherny, Robert D Moir, Maria H Ericsson, Xudong Huang, Christine Mavros, Jennifer A Coccia, Kyle Y Faget, Karlotta A Fitch, Colin L Masters, Rudolph E Tanzi, Leo T Chylack Jr, Ashley I Bush
  • The Lancet, Volume 361 Issue 9365 Page 1258, http://www.thelancet.com/search

 

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